Sigma 孕酮Progesterone

Sigma 孕酮Progesterone
产品编号 P8783 | CAS号 57-83-0 | SIGMA
英文名:Progesterone
中文名:1.孕甾酮 2.黄体酮 3.黄体素 4.孕酮  5.孕醇 6.黄体激素
Synonym: 4-Pregnene-3,20-dione
CAS Number 57-83-0
Empirical Formula (Hill Notation) C21H30O2
Molecular Weight 314.46
description:synthesized from materials derived from plant source
product line:BioReagent
form:powder
potency:0.1-20 ng/mL
mp:128-132 °C(lit.)
solubility :absolute ethanol: soluble1 mg/mL
suitability :uitable for cell culture

Application

用于细胞培养,研究细胞信号传导和基因表达的甾醇调控
Other Notes
由卵巢黄体产生的类固醇激素。
包装:1, 5, 25 g in glass bottle
Reconstitution
To prepare 20μg/ml stock solution, add 1ml absolute ethanol per mg progesterone, gently swirl to dissolve, add 49ml sterile medium per ml ethanol.
Physical form
室温下为粉末状;分成小份冻存,以避免使用时反复冷冻/解冻
Biochem/physiol Actions
诱导子宫内皮细胞的成熟和分泌活动;抑制排卵。孕酮与乳腺癌的病因有关。

Sigma人血管紧张素 II

Sigma人血管紧张素 II
产品编号 A9525 | CAS号 4474-91-3 | SIGMA

Angiotensin II human    ≥93% (HPLC), powder

CAS号 4474-91-3
分子式: C50H71N13O12
分子量 1046.18
assay    ≥93% (HPLC)
form    powder
total impurities    1.2-10.4% acetate
storage temp.  -20°C
Amino Acid Sequence
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe
Antibody Adsorbant
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH · 2CH3COOH · H2O
Analysis Note
肽含量不低于 75%
Biochem/physiol Actions
血管紧张素 (Ang) II 在调节心血管的血液动力学和结构中起重要作用。Ang II 在成人组织内的大部分已知效应均可归因于血管紧张素 II 类型 I (AT1) 受体。AT1 和 AT2 受体在药理学和生物化学性质上有差别,在心血管血液动力学和细胞生长方面表现出相反的效应。此外,肾素-血管紧张素和一氧化氮生成系统在心血管功能的调节中显示出相互作用的现象。Ang II 刺激血管生成,增加微血管密度。事实上,血管紧张素 II 是由血管紧张素转换酶对血管紧张素原的作用而生成;C-端-组氨酰-亮氨酸裂解。
保存条件: -20°C

Sigma丝裂霉素 C 来源于头状链霉菌

Sigma丝裂霉素 C 来源于头状链霉菌
产品编号 M0503-2mg | CAS号 50-07-7 | SIGMA

Frequently Asked Questions

Frequently Asked Questions are available for this Product.
Application
Mitomycin C is produced by a strain of actinomyces, Streptomyces caespitosus. It contains three anticancer moieties, quinine, urethane, and aziridine groups. It is used to generate mitotically inactive feeder cells in cell culture systems, such as the mitotically inactive fibroblasts used in embryonic stem cell systems.
Biochem/physiol Actions
DNA 合成、细胞核分裂和癌细胞的抑制剂。对革兰氏阳性菌、革兰氏阴性菌、抗酸杆菌有抗菌性。
Caution
This vial contains 2 mg Mitomycin C and 48 mg NaCl. Stock solutions should be filter sterilized and stored at 2-8°C in the dark. Solutions at pH 6-9 can be stored at 0-5°C for up to a week, but if a precipitate forms, a fresh solution should be prepared – the precipitated solution has been proven toxic to cells.
Preparation Note
Mitomycin C is soluble in water at .5 mg/mL, with a pH of 6.0-7.5. It undergoes rapid degradation in acidic solutions with pH<6, and is mostly likely to retain activity in solutions with a pH between 6-9.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information

Sigma 阿霉素 盐酸盐

Sigma 阿霉素 盐酸盐
产品编号 D1515 | CAS号 25316-40-9 | SIGMA

Frequently Asked Questions

Frequently Asked Questions are available for this Product.
包装:10 mg in glass bottle Biochem/physiol Actions
Naturally fluorescent anthracycline antibiotic, anticancer drug. Doxorubicin is a substrate of MRP1 which was first cloned from a DOX-resistant lung cancer cell line. Fluorescent property has been exploited for the measurement of drug efflux pump activities as well as resolving the important question of intracellular localization of various multidrug resistance proteins and the role of subcellular organelles (Golgi and lysosome) in the sequestration of drugs and its implication in drug resistant phenotypes.
法律信息
Adriamycin 为以下机构的注册商标: RDF Pharmacia & Upjohn S.P.A.
Protocols & Applications
Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information

Related Categories Antibiotics, Antibiotics A to Z, Antibiotics A-F, Antibiotics by Application, Antineoplastic and Immunosuppressive Antibiotics,

更多…
assay 98.0-102.0% (HPLC)
mp 216 °C (dec.)(lit.)
solubility H2O: soluble50 mg/mL, clear
Mode of action DNA synthesis | interferes
antibiotic activity spectrum viruses
storage temp. 2-8°C