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Harlan Teklad动物饲料The Concordat on Openness on Animal Research

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Harlan Teklad动物饲料The Concordat on Openness on Animal Research

The commitments

Signatories to the Concordat have agreed to be more open about their use of animals in research, and to abide by the following four commitments.

Commitment 1:
We will be clear about when, how and why we use animals in research

Commitment 2:
We will enhance our communications with the media and the public about our research using animals

Commitment 3:
We will be proactive in providing opportunities for the public to find out about research using animals

Commitment 4:
We will report on progress annually and share our experiences

Transparency agreement on animal research in the UK

The Concordat on Openness on Animal ResearchInotiv along with 122 UK organizations have so far signed the Concordat on Openness on Animal Research. Universities, charities, commercial companies, research councils, umbrella bodies and learned societies have all committed to help the public understand more about animal research.

Transparency agreement on animal research in the Netherlands

Op 2 november 2021 ondertekenden 15 organisaties die betrokken zijn bij dieronderzoek in Nederland het Nederlandse Transparantieakkoord Dieronderzoek met de belofte om op een meer open manier te communiceren over hoe dieren worden gebruikt in onderzoek. De groep ondertekenaars bestaat uit universiteiten, universitair medische centra, wetenschappelijke instituten, bedrijven en verenigingen.

On November 2, 2021, 15 organizations involved in animal research in the Netherlands  signed the Dutch Transparency Agreement on Animal Research with a commitment to communicate in a more open way about how animals are used in research. The group of signatories consists of universities, university medical centres, scientific institutes, companies, and associations.

Harlan Teklad动物饲料Mineral Adjusted Diets

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Harlan Teklad动物饲料Mineral Adjusted Diets

A few mineral adjusted formulas are shown below. Please contact us for additional formulas of this nature or for more information about altering the mineral profile of a diet. Read below for more information.

Formula examples:

  • TD.80396       Iron deficient diet
  • TD.85419       Zinc deficient diet
  • TD.88239       Potassium deficient diet
  • TD.95027       Low calcium diet (0.4% P)
  • TD.96348       Diet (20% lactose, 2% Ca, 1.25% P)
  • TD.92163       Selenium deficient diet
  • TD.95125       Iodine deficient (0.15% PTU)

Unique protein ingredients may be necessary to minimize background levels of certain minerals. Other steps taken to minimize background mineral contamination include the use of reagent grade minerals when necessary or omission of certain ingredients. Specialized mineral premixes may be used in these diets, or minerals are added individually to the diet in order to control the level of specific minerals.

With the exception of sodium, it is necessary to use refined ingredients to achieve the lowest possible levels of minerals in a diet.

From this mineral deficient base, various levels of minerals can be added back. Some formulas adjust multiple minerals, and other related nutrients.

Contact us to discuss other possibilities for the minerals listed above, and for those minerals not listed here.

Harlan Teklad动物饲料Rodent Diets

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Harlan Teklad动物饲料Rodent Diets

As a researcher, you want to have as much control as possible over what goes into your study animals. At Inotiv, we understand that. That is why we developed Teklad Global Rodent Diets® .

Teklad Global Rodent Diets® are a special integrated range of vegetarian laboratory rodent diets developed to be nutritionally complete for various life stages from breeding through long-term maintenance. Global rodent laboratory diets contain levels of protein, energy, vitamins and minerals that are more appropriate to the needs of modern biomedical research studies.

Furthermore, in global rodent diets particular attention has been placed on avoiding, as far as practical, ingredients that are reported to have adverse confounding effects on experimental results. This has resulted in a range of Teklad rodent laboratory diets that contain:

  • No fish meal
  • No meat meals or meat by-products
  • No alfalfa meal
  • No soybean meal or reduced levels
  • No animal fat

By excluding animal by-products, the presence of nitrosamines (a potential carcinogen) is avoided. Exclusion of alfalfa meal reduces chlorophyll, improving optical imaging clarity. Reduction or removal of soybean meal, together with elimination of alfalfa meal, minimizes levels of naturally-occurring phytoestrogens. Phytoestrogens interact with endogenous estrogens and potentially can affect studies in many research areas. Read more about this in these pieces:

Products

Teklad rodent diets Non-autoclavable form Autoclavable Irradiated
Teklad global 14% protein 2014 , 2014C 2914
Teklad global 16% protein 2016 , 2016C 2916
Teklad global 18% protein 2018 , 2018C 2018S , 2018SX 2918
Teklad global 19% protein extruded 2019 2019S 2919
Teklad global soy protein-free extruded 2020X 2020SX 2920X
Traditional diets see more see more see more

Not all products are stocked locally; extended lead time and additional fees may apply.
Many diets are available in certified format designated by a “C” following the product code. When diets are certified a representative sample is tested for a panel of contaminants. If not stocked as certified, certification can be made available upon request. Minimum order size and additional charges may apply.

Click here for recommendations on shelf life and storage

 

 

Traditional rodent diets were formulated decades ago based on understanding of rodent nutrition, ingredients, and diet manufacturing at the time. While traditional diets will supply the known nutrient needs of your laboratory animals, we recommend you consider the use of a diet from our newer global diet line for your modern research needs.

Teklad Global Rodent Diets® are modern formulas designed to reduce research variables. Specifically, these diets contain more appropriate nutrient levels, and limit or exclude ingredients that are reported to have effects on a wide variety of research endpoints.

  • Lower, more appropriate protein levels can improve survival and reduce morbidity
  • Vegetarian with no nitrosamines (a potential carcinogen)
  • Formulated to exclude alfalfa meal, greatly improving fluorescent imaging clarity
  • Formulated to exclude or lower soybean meal, thus minimizing the presence of isoflavones, the primary type of phytoestrogen found in lab animal diets
  • Extruded rodent diets dramatically reduce clumping and hardness after autoclaving (2018SX , 2019S , 2020SX ), and in general result in less diet waste and cleaner cages

Teklad rodent diets are natural-ingredient diets specifically formulated to provide the proper balance of all known nutrients considered essential for the growth, maintenance, and reproduction of rats, mice, gerbils and hamsters. These diets conform to the nutrient requirements for rodents established by the National Research Council (1995).

Teklad rodent diets provide uniform nutrition. They are fixed-formula diets designed to minimize the nutrient variances which otherwise could occur if the ingredient composition of a diet were altered from one batch to the next.

Protein is supplied primarily by plant sources. Supplemental amino acids are added to provide the proper amount and balance of essential amino acids. All rodent diets are fortified with vitamins and minerals to help support the regulation of body fluids and the proper functioning of body systems to ensure the adequate growth, maintenance, and reproduction of research rodents. Autoclavable diets are supplemented with additional vitamins to compensate for losses that occur during autoclaving. Since our diets are nutritionally complete and balanced, it is not necessary to add dietary supplements.

Standard natural ingredient rodent diets are complete diets for rats, mice, gerbils and hamsters, that should be allowed ad libitum access to the diet. Fresh water should be available at all times.

Harlan Teklad动物饲料Protein Adjusted Diets

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上海金畔生物科技有限公司代理Harlan Teklad动物饲料全线产品，欢迎访问Harlan Teklad动物饲料官网了解更多信息。
Harlan Teklad动物饲料Protein Adjusted Diets

A few protein adjusted formulas are shown below. Please contact us for additional formulas of this nature or for more information about altering the protein type or content of a diet.

Formula examples:

These diet examples are from a series of diets with the following features: casein-based, isocaloric (3.8 kcal/g) and matched for fat (5.5%), calcium (0.7%), and phosphorus (0.54%). There are other diets available from this series of diets, as well as other unique protein adjusted diets.

Casein is the most widely used refined protein source, but it is also possible to use other refined protein sources, such as “vitamin-free” test casein (alcohol extracted), lactalbumin, isolated soy protein, and egg white solids. These particular protein sources are usually used to achieve a specific research objective, rather than for routine use. For instance, vitamin-free test casein is most appropriately used in vitamin deficient diets, and egg white solids is most suitable for zinc or biotin deficient diets.

Adjusted protein diets usually range from “protein-free” (trace) to 60% protein, depending on the research.