TGF-β1 ELISA kit-价格-厂家-供应商-上海金畔生物科技有限公司

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      96 孔

    灵敏度:3.3 pg/ml (range 31.25 – 1000 pg/ml)测定时间:4小时应用:人、小鼠、大鼠和牛细胞培养上清液、血浆和血清中 TGF-β1含量的定量检测交叉反应:Human TGF-β1 (100%), TGF-β1.2 (2.23%), latent TGF-β1 (<0.71%) and <0.03%: TGF-β2, TGF-β3, LAP试剂盒包含:Microtiter plate, Conjugate, Antibody, Assay buffer 13, Assay buffer 30, Wash buffer concentrate, Standard, TMB Substrate, Stop solution 2其它参数:Transforming growth factor beta 1 is also known as TGFβ1, TGF β, and TGFB. The inactive form consists of a TGF-β1 homodimer that is non-covalently linked to a latency-associated peptide homodimer. The active form is a homodimer of mature TGF-β1 that is disulfide linked. The precursor is cleaved into mature TGF-β1 and the latency-associated peptide. Many cells can synthesize TGF-β1, which is secreted to function in proliferation, differentiation, transformation, signaling and apoptosis. This cytokine has been implicated in many diseases including diabetes, renal disease, chronic pulmonary obstructive disease, as well as many cancers including prostate, and colon. This protein is a potential tumor-specific cancer therapeutic. Specifically, as a stable soluble dimer, it selectively induces apoptosis in many transformed cells, but not in normal cells. The literature contains many reviews on the biology and function of TGF-β1.